Minghao Jiang | 姜 明昊

Rm L3-38, Laboratory Block
21 Sassoon Rd
Pok Fo Lam, Hong Kong
I am a second-year Ph.D. student at School of Biomedical Sciences, Li Ka Shing Faculty of medicine, The University of Hong Kong majoring in Bioinformatics. My research currently centers on two main topics: first, identifying novel structural variants to classify patients with B-cell acute lymphoblastic leukemia (B-ALL) using long-read sequencing; second, exploiting the mechanisms of APOBEC mutational signatures in ETV6::RUNX1/-like B-ALL. My work is supervised by Professor Jason Wong.
Prior to joining HKU, I obtained my Bachelor of Science degree in Bioinformatics from Harbin Medical University in 2019. Subsequently, I pursued my Master of Science degree in Biology at Shanghai Institute of Hematology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University in 2022, doing research about deciphering the mechanism of leukemogenesis across various subtypes (e.g., IGH::DUX4 and MEF2D fusions). Following that, I worked as a technician for 10 months at Shanghai Institute of Immunology, where my responsibilities included sequencing platform construction.
News
Nov 20, 2024 | I forgot to mention that Hongxin has published a preview titled Finish the unfinished: Chd1 resolving hexasome-nucleosome complex with FACT on 19 September. |
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Dec 1, 2023 | I am delighted to share that the manuscript titled Transcription factor 12 mediated self-feedback regulatory mechanism is required in DUX4 fusion leukemia has been accepted by the esteemed journal, Clinical and Translational Medicine, following an extensive review and revision process spanning nearly two years. I would like to express my sincere gratitude to Dr Zhihui Li, one of the co-authors, for her invaluable assistance. Without her contributions, I believe it would not have been possible for us to have this entire story accepted by CTM. |
Nov 8, 2023 | Recently, I purchased a new Mac mini equipped with the M2 Pro chip for daily work needs because my old MacBook Pro (Intel, 2018) is broken due to overheat. |
Selected publications
- Primary assessment of the diversity of Omicron sublineages and the epidemiologic features of autumn/winter 2022 COVID-19 wave in Chinese mainlandFrontiers of Medicine, 2022
- A comprehensive benchmarking of differential splicing tools for RNA-seq analysis at the event levelBriefings in Bioinformatics, 2023
- Transcription factor 12-mediated self-feedback regulatory mechanism is required in DUX4 fusion leukaemiaClinical and Translational Medicine, 2023